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Biovision Recombinant

Biovision Complete Product Catalog

 

 

  1. Caspases are a family of protease enzymes that play crucial roles in programmed cell death (apoptosis) and inflammation. They are involved in various cellular processes such as cell differentiation, proliferation, and immune response.
  2. Caspases are categorized into two main groups: initiator caspases (such as caspase-8 and caspase-9) and executioner caspases (such as caspase-3, caspase-6, and caspase-7).
  3. Initiator caspases are responsible for initiating apoptosis by activating executioner caspases, which then carry out the dismantling of the cell.
  4. Recombinant Biovision caspases are caspases that are produced using recombinant DNA technology. Recombinant proteins are generated by expressing the gene encoding the protein of interest in a host organism, typically bacteria, yeast, or mammalian cells.
  5. Our recombinant caspases are used for research to study apoptosis, inflammation, and other cellular processes. They offer several advantages over native caspases purified from tissues, including higher purity, greater yield, and consistency between batches.
  6. BioVision offers a range of recombinant caspases for research purposes. These recombinant proteins are used to investigate the molecular mechanisms of apoptosis and inflammation, as well as to develop novel therapeutic strategies for diseases associated with dysregulated cell death pathways.
  7. Biovision spases are important protease enzymes involved in cell death and inflammation, and recombinant caspases are artificially produced versions of these enzymes that are used in research to study their functions and regulatory mechanisms.
  8. BioVision offers recombinant caspases as part of its portfolio of research tools for investigating apoptosis, inflammation, and related cellular processes.

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  • PDPK1, Active

    Biovision | PDPK1, Active | 7706

    The initial steps in insulin signal transduction occur at the plasma membrane and lead to the activation of phosphatidylinositide (PtdIns) 3-kinase and the formation of PtdIns(3,4,5,)P3 in the inner leaflet of the plasma membrane which is then converted...

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  • PDGFR beta, Active

    Biovision | PDGFR beta, Active | 7770

    PDGFRb (platelet-derived growth factor receptor b) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRb deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function (1)...

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  • PDCD1LG2, human recombinant

    Biovision | PDCD1LG2, human recombinant | 7337

    Programmed cell death 1 ligand 2, also known as PDCD1LG2, is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell...

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  • PCNA, human recombinant

    Biovision | PCNA, human recombinant | 4835

    Expression of proliferating cell nuclear antigen (PCNA) or cyclin or polymerase auxiliary protein is elevated in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and...

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  • PARP-1, human recombinant

    Biovision | PARP-1, human recombinant | 4992

    Poly-ADP-ribose metabolism plays a major role in a wide range of biological processes, such as maintenance of genomic stability, transcriptional regulation, energy metabolism and apoptosis. PARP1 Enzyme, is highly purified and enzymatically active human...

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  • PAK7, Active

    Biovision | PAK7, Active | 7727

    The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement...

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  • PAK4, Active

    Biovision | PAK4, Active | 7707

    PAK4 is a recently identified member of the p21-activated kinases (PAKs) which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, cdc...

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  • P38delta, Active

    Biovision | P38delta, Active | 7754

    Mitogen-activated protein kinase (MAPK) cascades represent one of the major signal systems used by eukaryotic cells to transduce extracellular signals into cellular responses, and involved in a wide variety of cellular processes such as proliferation,...

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  • p38alpha, Active

    Biovision | p38alpha, Active | 7756

    p38a (SAPK2A) is a member of the p38 MAPK family which are activated by various environmental stresses and proinflammatory cytokines (1). The activation of p38 requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation...

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  • OSTF1, human recombinant

    Biovision | OSTF1, human recombinant | 7336

    Osteoclast-stimulating factor-1 (OSTF1) is an intracellular protein produced by osteoclasts that indirectly induces osteoclast (OCL) formation and bone resorption. OSTF1 is highly expressed in OCL and contains structural domains such as SH3 and ankyrin...

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  • Osteopontin, human recombinant

    Biovision | Osteopontin, human recombinant | 7335

    Osteopontin (OPN), also known as Secreted phosphoprotein 1 (SPP1), is a human gene product which is conserved in other species. This protein is glycoprotein that was first identified in osteoblasts and plays an important role in bone remodeling, immune...

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  • Notch-2, mouse recombinant

    Biovision | Notch-2, mouse recombinant | 7531

    Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch...

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  • Notch-1, mouse recombinant

    Biovision | Notch-1, mouse recombinant | 7530

    Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch...

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  • NME3, human recombinant

    Biovision | NME3, human recombinant | 7825

    NME3, also known as, a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. It is important for the synthesis of nucleoside triphosphates and may play a role in...

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  • NME2, human recombinant

    Biovision | NME2, human recombinant | 7824

    NME2, also known as NM23B, is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of...

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  • NME1, human recombinant

    Biovision | NME1, human recombinant | 7823

    Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their levels have been alternatively associated with reduced or increased metastatic...

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  • NFNB, bacterial recombinant

    Biovision | NFNB, bacterial recombinant | 7830

    NFNB, also known as NFSB, shows the ability to reduce quinines. This protein is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. It also capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954...

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  • Nesfatin-1, rat recombinant

    Biovision | Nesfatin-1, rat recombinant | 4914

    Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the regulation of the feeding behavior. Intracerebroventicular...

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  • Nesfatin-1, mouse recombinant

    Biovision | Nesfatin-1, mouse recombinant | 4913

    Nesfatin-1, a polypeptide produced by cleavage of the NEFA/nucleobindin-2 (NUCB2), is a secreted protein, expressed in the appetite-control hypothalamic nuclei. Nesfatin is involved in the regulation of the feeding behavior. Intracerebroventicular...

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  • NEK7, Active

    Biovision | NEK7, Active | 7717

    Nek7 is a member of the NIMA (never in mitosis, gene A) family of serine/threonine kinases. In contrast to the other documented NIMA-related kinases, Nek7 harbor its catalytic domain in the C-terminus of the protein. Immunofluorescence studies suggest...

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  • NEK6, Active

    Biovision | NEK6, Active | 7716

    Nek6 is a serine/threonine kinase that is a member of the Nek family of protein kinases that share an amino-terminal catalytic domain related to NIMA (never in mitosis, gene A) family (1). Nek6 is a nuclear and cytoplasmic kinase that is required for...

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  • NEK2, Active

    Biovision | NEK2, Active | 7719

    Nek 2 is closely related in its catalytic domain to the serine/threonine protein kinase NIMA of Aspergillus nidulans that is required for entry into mitosis and may function in parallel to the universal mitotic inducer p34cdc2. Like NIMA, the Nek2...

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  • NEDD8-AMC

    Biovision | NEDD8-AMC | 4843

    Prepared by the C-terminal derivatisation of NEDD8 with 7-amino-4-methylcoumarin. NEDD8-AMC acts as a useful and sensitive fluorogenic substrate for deNEDDylating enzymes, including NEDP1 and UCH-L3. It is a useful reagent for the study of deNEDDylating...

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  • NAD Kinase, human recombinant

    Biovision | NAD Kinase, human recombinant | 7560

    NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to...

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  • MRCK beta, Active

    Biovision | MRCK beta, Active | 7772

    Myotonic Dystrophy Kinase-Related cdc42-binding kinase (MRCKb) belongs to the DMPK subfamily (1). The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42,...

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  • Mouse Recombinant GSTMu 1

    Biovision | Mouse Recombinant GSTMu 1 | 6348

    GSTM1 is a glutathione S-transferase that belongs to the mu class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the...

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  • Mouse Recombinant GSTM 1

    Biovision | Mouse Recombinant GSTM 1 | 6349

    GSTM1 is a glutathione S-transferase that belongs to the mu class. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the...

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  • Mouse Recombinant DHFR

    Biovision | Mouse Recombinant DHFR | 6383

    Dihydrofolate reductase (DHFR) is a member of the reductase family of enzymes that is ubiquitously expressed in all organisms. DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and it is essential for the synthesis of...

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  • MET, Active

    Biovision | MET, Active | 7771

    MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kd () and 145 kd (). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue (1). Hepatocyte...

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  • Mep1b, mouse recombinant

    Biovision | Mep1b, mouse recombinant | P1041

    MEP1B, also known as meprin A subunit beta, is a member of the astacin family of zinc endopeptidases 1, 2. It is disulfide-linked, tetrameric metalloendopeptidases in renal brush border membranes. It is highly regulated, secreted, and cell-surface...

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  • MAPKAPK3, Active

    Biovision | MAPKAPK3, Active | 7755

    MAPKAPK3 has a single potential SH3-binding site in the proline-rich N terminus, a putative ATP-binding site, 2 MAP kinase phosphorylation site motifs, and a putative nuclear localization signal. It shares 72% nucleotide and 75% amino acid identity with...

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  • MAPKAPK2, Active

    Biovision | MAPKAPK2, Active | 7737

    MAPKAP kinase2 is a Ser/Thr protein kinase, which is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory...

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  • MAGE-1, human recombinant

    Biovision | MAGE-1, human recombinant | 4820

    0Biovision | 4820 | MAGE-1 human recombinant DataSheetBiomolecule/Target: N/ASynonyms: Melanoma-associated antigen 1, MAGE-1 antigen, Antigen MZ2-E, Cancer/testis antigen 1,1, CT1,1, MAGEA1, MAGE1, MAGE1A, MGC9326,Alternates names: N/ATaglines: A...

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  • Lyn B, Active

    Biovision | Lyn B, Active | 7715

    Lyn is a 56 kd tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck and the v-yes protein as well as to the gene products of v-fgr and v-src. Northern hybridization analysis showed that a 3.2-kilobase Lyn mRNA was...

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