Biovision Recombinant

Biovision | CD7, human recombinant | 7316

T-cell antigen CD7, also known as CD7, is a type I transmembrane glycoprotein that is expressed on pluripotential hemopoietic cells, most human thymocytes and some peripheral blood T cells. The CD7 molecule is absent in a subset of human T cells under...

Biovision | CD68, human recombinant | 7343

Macrosialin, also known as CD68, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and...

Biovision | CD5, human recombinant | 7315

CD5 is a good immunohistochemical marker for T-cells, although not as sensitive as CD3. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells...

Biovision | CD46, human recombinant | 7314

Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats...

Biovision | CD3G, human recombinant | 7313

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role...

Biovision | CD3E, human recombinant | 7342

CD3E is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen...

Biovision | CD300C, human recombinant | 7312

CMRF35-like molecule 6, also known as CD300C, belongs to the CD300 family. The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. Recombinant human CD300C...

Biovision | CD300A, human recombinant | 7341

CD300A belongs to the CD300 family and contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes...

Biovision | CD274, mouse recombinant | 7311

CD274, also known as programmed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interacts with...

Biovision | CD247, human recombinant | 7340

T-cell surface glycoprotein CD3 zeta chain, also known as CD247, belongs to the CD3Z/FCER1G family. CD247 is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms...

Biovision | CD244, human recombinant | 7339

CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation...

Biovision | CD226, human recombinant | 7310

CD226 is a 65 kDa glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and...

Biovision | CD200, human recombinant | 7309

CD200 is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers...

Biovision | CD1E, human recombinant | 7308

CD1E is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of...

Biovision | CD-14, mouse recombinant | 4938

CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macrophages and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor...

Biovision | CD-14, human recombinant | 4937

CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macro¬pha¬ges and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor...

Biovision | CCL3L1, human recombinant | 7305

CCL3L1 is a small cytokine belonging to the CC chemokine. This protein is involved in immunoregulatory and inflammatory processes. It binds to several chemokine receptors including chemokine binding protein 2 (CCBP2 or D6) and chemokine (C-C motif)...

Biovision | CCL21, human recombinant | 7338

CCL21 is member of the chemokine superfamily and the subfamily of CC chemokines that has an aspartate cysteine-cysteine-leucine motif near its amino-terminus. This protein is involved in inhibits hemopoiesis and stimulates chemotaxis. CCL21 is...

Biovision | CBR4, human recombinant | P1156

CBR4 belongs to the short-chain dehydrogenase/reductase family. The formation of heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity for o- and p-quinones. It plays a role in biosynthesis of fatty acids in...

Biovision | Cathepsin H (active, human) | 1023

A more basic protein than Cathepsin B or L. Functions as both an aminopeptidase and endopeptidase. Cathepsin H, like cathepsin L and B, is involved in the catabolism of proteins in the lysosomal system.Biovision | 1023 | Cathepsin H active human...

Biovision | Cathepsin G, Human Neutrophil | 4713

Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It...

Biovision | Cathepsin D (active, human) | 1022

Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally cathepsin D has been associated...

Biovision | Cathepsin B (active, human) | 1021

Cathepsin B is a lysosomal cysteine protease. It is implicated in playing a role in protein degradation, arthritis, apoptosis, and cancer.Biovision | 1021 | Cathepsin B active human DataSheetBiomolecule/Target: Cathepsin BSynonyms: Cathepsin B (active,...

Biovision | Catalase, Human Erythrocytes | 4712

Composed of four identical subunits each with a molecular weight of 59,700. Catalyzes the reaction 2HO to HO+O. Catalase, along with the superoxides dismutase and glutathione peroxidase, controls the levels of oxygen-derived free radicals in mammalian...

Biovision | Caspases Group III, Active Human | K243

Caspase family consists of more than 10 members. Based on their extended substrate specificities, these enzymes were divided into three major groups: Group I (contains caspase-1,-4,-5), Group II (contains caspase-2,-3,-7), and Group III (contains...

Biovision | Caspases Group II, Activ Human | K242

Caspase family consists of more than 10 members. Based on their extended substrate specificities, these enzymes were divided into three major groups: Group I (contains caspase-1,-4,-5), Group II (contains caspase-2,-3,-7), and Group III (contains...

Biovision | Caspase-9 Proform, human recombinant | 1089P

Caspase-9 is a member of the caspase family of cysteine proteases. Caspase-9 exists in cells as an inactive proenzyme. Proteolytic processing of this inactive proenzyme generates the large and small subunits which, when assembled as a tetramer (a pair of...

Biovision | Caspase-3 Proform, mouse recombinant | 1183P

Caspase-3 (also know as CPP32, Yama and apopain) is a member of the caspase family of cysteine proteases. Caspase-3 exists in cells as an inactive 32 kDa proenzyme. Proteolytic processing of this inactive proenzyme generates the 17 kD and 12 kD subunits...

Biovision | CAMK4, Active | 7740

CAMK4 belongs to the serine/threonine protein kinase family and Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution. Sikela et al. identified that brain...

Biovision | CAMK1G, Active | 7736

CLICK-III/CaMKIG is a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK), an isoform of the CaMKI family with an extended C-terminal domain ending with CAAX motif (where AA is aliphatic acid). As expected from the similarity...

Biovision | CAMK1d, Active | 7713

Calcium/calmodulin-dependent protein kinase ID (CAMK1D), or a novel Ca2+/calmodulin-dependent kinase I-like kinase (CKLiK), showed kinase activity and that the activity was enhanced by Ca(2+) and calmodulin. Using a novel antibody generated against the...

Biovision | CAMK1b, Active | 7729

Many of the effects of calcium are mediated via its interaction with calmodulin and the subsequent activation of Ca(2+)/calmodulin-dependent (CaM) kinases. CaM kinases are involved in a wide variety of cellular processes including muscle contraction,...

Biovision | Calretinin, murine recombinant | 4809

Calretinin is an intraCellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to...

Biovision | Calmodulin, human recombinant | 7838

Calmodulin (CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions. CaM mediates processes such as inflammation, metabolism, apoptosis,...

Biovision | C1 Esterase inhibitor, Human Plasma | 7299

A single chain glycoprotein which inhibits C1, C1r, C1s, plasma kallikrein, Factors XIa. XIIa, and plasmin. Present in plasma at 16-33 mg per 100 ml. C1 esterase inhibitor deficiency is a rare condition resulting in facial swelling and abdominal cramping...

Biovision | BRK, Active | 7708

BRK is another member of the non-receptor tyrosine kinases (PTKs) that contains an amino terminal SH3 and SH2 domains as well as the catalytic domain (1). Although BRK shows strongest sequence similarity to members of the Src family, there are several...

Biovision | BRD3 bromodomain (1-416 aa) (His-Tag), human recombinant | 7407

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This...

Biovision | BRD2 bromodomain (1-455 aa) (His-Tag), human recombinant | 7406

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This...

Biovision | BRD1 bromodomain (556-688 aa) (His-Tag), human recombinant | 7405

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This...

Biovision | BPTF bromodomain (2796-2907 aa) (GST-tagged), Human recombinant | 7662

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This...

Biovision | BNP, human | 4875

Natriuretic Peptide Precursor B acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular...

Biovision | BMX, Active | 7732

The BMX gene encodes a novel non receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells (1). Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine...

Biovision | BMP8B, human recombinant | 7304

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of...

Biovision | BMP-3b/GDF-10, human recombinant | 7303

GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may...

Biovision | BLVRA, human recombinant | 7827

BLVRA, also known as biliverdin reductase A, belongs to the gfo/idh/mocA family. This protein is an enzyme that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. (Bilirubin + NAD (P)...

Biovision | BLK, Active | 7723

Blk, also known as B lymphoid kinase, is a 55 kd tyrosine kinases with a SH3, SH2 and catalytic domains that contain consensus sequences of the src protein tyrosine kinase family. Blk is expressed specifically in the B cell lineage and plays a role in...

Biovision | Bacterial Recombinant SurA | 6381

SurA is a periplasmic peptidyl-prolyl isomerase (PPIase) and chaperone of Escherichia coli and other Gram-negative bacteria. This protein is a major factor in the biogenesis of beta-barrel outer membrane proteins (OMPs) and plays an integral role in cell...

Biovision | Bacterial Recombinant MDH | 6357

Malate dehydrogenase (MDH) belongs to the LDH/MDH superfamily and MDH type 1 family. This enzyme catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (reversible reaction). This reaction is part of many metabolic pathways,...

Biovision | Bacterial Recombinant GOR | 6380

Gor, also known as Glutathione oxido-reductase, belongs to the class-I pyridine nucleotide disulfide oxidoreductase family. The main function of this protein is to maintain high levels of reduced glutathione in the cytosol. With the concomitant oxidation...

Biovision | B4GalT1, soluble fragment, Human Recombinant | P1222

1,4-galactosyltransferase 1 was the first mammalian glycosyltransferase to be isolated and cloned. 4GalT1 is a member of a homologous family of seven 1,4-galactosyltransferases, 4Gal-T1 – T7, that catalyze the transfer of galactose from UDP-Gal to...

Biovision | B3GNT6, soluble fragment, Human Recombinant | P1221

­1,3­N­acetylglucosaminyltransferase 6 (3GnT6) transfers N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to N-acetylgalactosamine (GalNAc). 3GnT6 is also known as the core 3 synthase, because it creates the core 3 oligosaccharide structure in the...

Biovision | Azurocidin, Human Neutrophil (Cationic protein 37) | 7287

The gene for azurocidin is located on the short arm of chromosome 19 and is in a cluster with the genes for proteinase 3 and elastase. All three proteins are serine protease homologues; azurocidin, however, lacks enzymatic activity. It is an antibiotic...