Product Description
Biovision | Active LAMP2/CD107b, Human Recombinant | P1740
Description: LAMP2 (CD107b) is a membrane glycoprotein that functions in the protection, maintenance, and adhesion of the lysosome. LAMP2 plays an important role in chaperone-mediated autophagy to mediate lysosomal degradation of proteins in response to stress. LAMP2 may also have a role in tumor cell metastasis.
Biomolecule/Target:
Synonyms: Lysosomal Associated Membrane Protein 2; Lysosome-Associated Membrane Glycoprotein 2; CD107 Antigen-Like Family Member B; LAMP-2; LGP-96; LGP110; LAMPB; DND
Alternates names:
Taglines: Plays a role in lysosomal protein degradation
NCBI Gene ID #: 3920
NCBI Gene Symbol: Human
Accession #: P13473
Recombinant: True
Source: Human cells
Purity by SDS-PAGE: > 95% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.
Activity (Specifications/test method):
Biological activity: Immobilized human Galectin-3 (at 1.5 μg/ml, 100 μl/well) can bind Active LAMP2/CD107b with an ED50 of 12.73 μg/ml
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 33.9 kDa (predicted); 78 kDa (observed)
Concentration:
Appearance: Lyophilized protein
Physical form description:
Reconstitution Instructions:
Amino acid sequence: Leu 29 to Ile 375 with C-terminal 6xHis Tag
Handling: Centrifuge the vial prior to opening.
Usage: