Product Description
BCL-2 was the first anti-death gene discovered with far reaching implications in tumor biology. It regulates cell death by either inhibiting (anti-apoptotic) or inducing (pro-apoptotic) apoptosis. The BCL-2 protein is the founding member of the BCL-2 family of apoptosis regulators and was the first apoptosis modulator to be associated with cancer. It suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL-2 regulates cell death by controlling the mitochondrial membrane permeability.
Biovision | P1627 | BCL2 Protein, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: Protein phosphatase 1,Regulatory subunit 50,BCL - XL,BCL2 apoptosis regulator,B - cell CLL/lymphoma 2,PPP1R50
Alternates names: Protein phosphatase 1,Regulatory subunit 50,BCL - XL,BCL2 apoptosis regulator,B - cell CLL/lymphoma 2,PPP1R50
Taglines: Human Recombinant protein
NCBI Gene ID #: 596
NCBI Gene Symbol: 231632
Gene Source: Human
Accession #: NP_000624.2, P10415
Recombinant: TRUE
Source: E.coli
Purity by SDS-PAGE: ≥ 95% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 25 kDa
Concentration:
Appearance: Liquid
Physical form description:
Reconstitution Instructions:
Amino acid sequence: The target protein is expressed with sequence (Ala2-Asp211) of human BCL2.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans