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Product Description
Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1), a growth suppressor that negatively regulates CDK2 activity, has been implicated in various types of cancer. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation.
Biovision | P1630 | CDK2AP1 Protein, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: CDKA1,CDK2 associated protein 1,CDK2 A1,DOC1,Cyclin-dependent kinase 2
Alternates names: CDKA1,CDK2 associated protein 1,CDK2 A1,DOC1,Cyclin-dependent kinase 2
Taglines:
NCBI Gene ID #: 8099
NCBI Gene Symbol: O14519
Gene Source: Human
Accession #: NP_004633, O14519
Recombinant: FALSE
Source: E.coli
Purity by SDS-PAGE: ≥ 95% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 16.6 kDa
Concentration:
Appearance: Sterile Filtered colorless solution
Physical form description: Liquid
Reconstitution Instructions:
Amino acid sequence: 1-152 aa
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
