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Product Description
Activin A receptor type 2B (ACVR2B) is a constitutively active transmembrane serine/threonine kinase that forms a complex with type I activin receptors to transduce activin signaling. Activin signaling is responsible for regulating many physiological and pathological processes including neuronal differentiation and survival, hair follicle development, wound healing, extracellular matrix production, immunosuppression, and carcinogenesis.
Biovision | P1731 | Human CellExp ACVR2B (Active), Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: Activin A Receptor Type 2B; ACTR-IIB; ACTRIIB; HTX4
Alternates names: Activin A Receptor Type 2B; ACTR-IIB; ACTRIIB; HTX4
Taglines: Constitutively active receptor serine/threonine kinase that regulates many physiological processes
NCBI Gene ID #: 93
NCBI Gene Symbol:
Gene Source: Human
Accession #: Q13705
Recombinant: True
Source: Human Cells
Purity by SDS-PAGE: > 95% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 1.0 EU per ug as determined by the LAL method
Activity (Specifications/test method): Immobilized Activin A at 5 ug/ml (100 ul/well) can bind Human ACVR2B. The ED50 of Human ACVR2B is 20.58 ng/ml
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 41.3 kDa calculated; 60 kDa observed
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions:
Amino acid sequence: Ser 19 to Thr 134 with C-terminal Fc & 6xHis Tag
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
