Product Description
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Biovision | P1326 | Human CellExp™ BCMA / TNFRSF17, Fc Tag, Human recombinant DataSheet
Biomolecule/Target :TNFRSF17
Synonyms: TNFRSF17, CD269, BCM, BCMA
Alternates names: TNFRSF17, CD269, BCM, BCMA
Taglines: A member of the TNF receptor superfamily
NCBI Gene ID #: 608
NCBI Gene Symbol: TNR17
Gene Source: Human
Accession #: Q02223
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGE: ≥95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1 EU/ug
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: Immobilized Biotinylated Human BAFF, His Tag at 1 ug/mL (100 uL/well) can bind Human BCMA, Fc Tag with a linear range of 0.1-0.8 ng/mL.
Results: N/A
Binding Capacity: Immobilized Biotinylated Human BAFF, His Tag at 1 ug/mL (100 uL/well) can bind Human BCMA, Fc Tag with a linear range of 0.1-0.8 ng/mL.
Unit Definition: N/A
Molecular Weight: 32 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 um filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 ug/ml.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans