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Product Description
Beta 2 Microglobulin is a component of the class I major histocompatibility complex (MHC). It presents the antigenic peptides to the immune system. It is present in small amounts in serum, csf, and urine of normal people and to a much greater degree in the urine and plasma of patients with tubular proteinaemia, renal failure or kidney transplants. The levels of Beta 2 Microglobulin are increased in multiple myeloma. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions.
Biovision | P1611 | Human CellExp™ Beta 2 Microglobulin DataSheet
Biomolecule/Target :
Synonyms: B2M
Alternates names: B2M
Taglines: A component of the class I major histocompatibility complex
NCBI Gene ID #: 567
NCBI Gene Symbol:
Gene Source: Human
Accession #: P61769
Recombinant: TRUE
Source: HEK293 cells
Purity by SDS-PAGE: ≥ 97% by SDSPAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 0.1 EU/ug of the protein as determined by LAL method
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: The protein migrates as a ~12-13 kDa band in SDS-PAGE
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized protein
Reconstitution Instructions: Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.
Amino acid sequence: aa Ile21-Met119
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
