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Product Description
CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16) , CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.
Biovision | P1496 | Human CellExp™ CD300c / LMIR2, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: CD300C, CLM-6, CMRF35-A1, CMRF-35, CMRF35A, IGSF16
Alternates names: CD300C, CLM-6, CMRF35-A1, CMRF-35, CMRF35A, IGSF16
Taglines: Present on monocytes, neutrophils, and some T and B lymphocytes
NCBI Gene ID #: 10871
NCBI Gene Symbol: CD300C
Gene Source: Human
Accession #: Q08708
Recombinant: True
Source: HEK 293 cells
Purity by SDS-PAGE: >95%
Assay: SDS-PAGE
Purity:
Assay #2:
Endotoxin Level: Less than 1.0 EU per ug by the LAL method.
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.7 kDa. The protein migrates as 25-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Concentration:
Appearance: Lyophilized powder
Physical form description: Lyophilized
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Amino acid sequence: AA Gly 21 - Arg 183
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
