Euro
USD
British Pound
NULL
Product Description
The GFRA2 receptor is a surface receptor attached to the cell membrane by a glycosylphosphatidylinositol linkage. GFRA2 is a receptor for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) and mediates activation of the RET receptor tyrosine kinase. GFRA2 is a candidate target for the study of RET-associated diseases.
Biovision | P1736 | Human CellExp™ GFRA2 / GDNFRB, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: GDNF Family Receptor Alpha-2; GDNF Receptor Beta; Neurturin Receptor Alpha; RET Ligand 2
Alternates names: GDNF Family Receptor Alpha-2; GDNF Receptor Beta; Neurturin Receptor Alpha; RET Ligand 2
Taglines: Mediates activation of RET signaling
NCBI Gene ID #: 2675
NCBI Gene Symbol:
Gene Source: Human
Accession #: O00451
Recombinant: True
Source: HEK293 cells
Purity by SDS-PAGE: > 95% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 1.0 EU per ug as determined by the LAL method
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: ~60 to 85 kDa due to glycosylation
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions: Reconstitute using sterile deionized water. Do not vortex.
Amino acid sequence: Ser 22 to Ser 441 with C-terminal 6xHis Tag
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
