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Product Description
Structural protein that makes short spikes at the surface of the virus. It contains receptor binding and receptor-destroying activities and mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps to prevent self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. It seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.
Biovision | P1527 | Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE) DataSheet
Biomolecule/Target :
Synonyms: Hemagglutinin-esterase, HE protein, E3 glycoprotein, HE
Alternates names: Hemagglutinin-esterase, HE protein, E3 glycoprotein, HE
Taglines: Structural protein that makes short spikes at the surface of the virus.
NCBI Gene ID #:
NCBI Gene Symbol: HE
Gene Source: Coronavirus
Accession #: P15776
Recombinant: TRUE
Source: Yeast
Purity by SDS-PAGE: >90%
Assay: SDS - PAGE
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 47.7 kDa (N-terminal 6xHis-tag)
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized
Reconstitution Instructions: Centrifuge the vial briefly. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.
Amino acid sequence: aa 19-424
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
