Product Description
Fibroblast activation protein (FAP), also known as seprase, is a homodimeric integral protein gelatinase belonging to the serine protease family. FAP has been implicated in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
Biovision | P1702 | Recombinant Human Fibroblast Activation Protein DataSheet
Biomolecule/Target :
Synonyms: Fibroblast activation protein, DPPIV Protein, DPPIV, FAPA, Fapalpha Protein, SIMP Protein, Prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, Fibroblast activation protein alpha, FAPalpha, Gelatine degradation protease FAP, Integral membrane serine protease, Post-proline cleaving enzyme, Serine integral membrane protease, SIMP, Surface-expressed protease, Seprase
Alternates names:
Taglines: Active Human FAP with C-terminal His-Tag
NCBI Gene ID #: 2191
NCBI Gene Symbol:
Gene Source: Human
Accession #: Q12884
Recombinant: True
Source: Baculovirus
Purity by SDS-PAGE: ≥ 90% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 1 EU per 1 ug of protein as determined by LAL method
Activity (Specifications/test method): Specific activity is > 5,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyzes 1.0 pmole of Z-GP-AMC per minute at pH 7.5, at 37 °C.
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 86.1 kDa
Concentration: 0.25 mg/mL
Appearance: Liquid protein
Physical form description: Liquid
Reconstitution Instructions:
Amino acid sequence: The target is expressed with the sequence from amino acid 26 to 760 with a His-Tag at the C-terminus
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans