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Product Description
The polymeric immunoglobulin receptor is a carrier that transports IgA and IgM across epithelium. The human pIgR has been implicated as a prognostic biomarker for hepatocellular carcinoma progression and metastasis.
Biovision | P1701 | Recombinant Human pIgR Protein DataSheet
Biomolecule/Target :
Synonyms: FLJ22667 MGC125361; MGC125362 Polymeric immunoglobulin receptor, PIGR, PIgR, Poly-Ig receptor, Hepatocellular carcinoma-associated protein TB6, polymeric immunoglobulin receptor precursor
Alternates names:
Taglines: Binds and transports polymeric IgA and IgM
NCBI Gene ID #: 5284
NCBI Gene Symbol:
Gene Source: Human
Accession #: P01833
Recombinant: False
Source: Baculovirus
Purity by SDS-PAGE: ≥ 95% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)
Activity (Specifications/test method):
Biological activity: Measured by its binding ability in a functional ELISA with Human IgM. The ED50 range ≤10 ug/ml.
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 68.9 kDa
Concentration: 1 mg/mL
Appearance: Liquid protein
Physical form description:
Reconstitution Instructions:
Amino acid sequence: The target is expressed with the sequence (Lys1-Arg638) of Human p!gR with a His tag at the C-terminus.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
