Native Proteins

Biovision | Hemopexin, Rat Serum | 7545

Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant...

Biovision | Hemopexin, Human Plasma | 7544

Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant...

Biovision | Hemocyanin-Keyhole Limpet (KLH), Native | 6288

Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been...

Biovision | Hemocyanin-Keyhole Limpet (KLH) subunits, solution | 6287

Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been...

Biovision | Hemocyanin-Keyhole Limpet (KLH) subunits, powder | 6286

Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been...

Biovision | Haptoglobin, Human Plasma (Mixed Type) | 7535

An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the...

Biovision | Haptoglobin, (Phenotype 2-2) Human Plasma | 7537

Haptoglobin 2-2 (Hp 2-2) is the least effective of the three haptoglobin phenotypes in binding free hemoglobin and therefore provides less antioxidant benefits than Hp 1-1. Hp 2-2 is associated with renal failure, familial epilepsy, hypertension,...

Biovision | Haptoglobin, (Phenotype 1-1) Human Plasma | 7536

Of the three haptoglobin phenotypes, Hp 1-1 is the most effective in binding free hemoglobin and in suppressing the inflammatory responses associated with free hemoglobin. Hp 1-1 protects against vascular complications in diabetes, is associated with...

Biovision | Fibrinogen (plasminogen depleted), Human Plasma | 7692

Fibrinogen is an acute phase protein that is part of the coagulation cascade of proteins. The end result of the cascade is the production of thrombin that converts fibrinogen to fibrin. Thrombin rapidly proteolysis fibrinogen, releasing fibrinopeptide A...

Biovision | Fibrinogen (Pg, Fn & vWF depleted), Human Plasma | 7694

Fibrinogen is an acute phase protein that is part of the coagulation cascade of proteins. The end result of the cascade is the production of thrombin that converts fibrinogen to fibrin. Thrombin rapidly proteolysis fibrinogen, releasing fibrinopeptide A...

Biovision | Fibrinogen (Pg & vWF depleted), Human Plasma | 7693

Fibrinogen is an acute phase protein that is part of the coagulation cascade of proteins. The end result of the cascade is the production of thrombin that converts fibrinogen to fibrin. Thrombin rapidly proteolysis fibrinogen, releasing fibrinopeptide A...

Biovision | Factor XIIa, Human Plasma | 7691

Human Factor -XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and prekallikrein are thought to be involved in a reciprocal activation mechanism in which Factor XIIa activates...

Biovision | Factor XII, Human Plasma | 7690

Human Factor XII is a single chain glycoprotein with a molecular weight of about 80,000. Once activated, principally from the action of kallikrein, Factor XII is converted into an active serine protease (Factor -Xlla) that functions in the in vivo...

Biovision | Factor Xa, Human Plasma | 7689

Factor Xa is a serine endoproteinase and a member of the S1 peptidase family. Factor Xa plays a critical role in the coagulation cascade by catalyzing the proteolytic conversion of prothrombin to active thrombin. Factor Xa’s prothrombin conversion...

Biovision | Factor X, Human Plasma | 7688

Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a disulfide bond. Prior to secretion into plasma, post-translational modifications produce 11...

Biovision | Factor VIIa, Human Plasma | 7687

Human factor VII is a single chain plasma glycoprotein, and is a zymogen in its native form. Proteolytic activation of factor VII, yields the enzyme factor VIIa, which when bound to the integral membrane protein tissue factor, forms an enzyme complex...

Biovision | Factor VII, Human Plasma | 7686

Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid...

Biovision | Elastase, Human Neutrophil | 4716

Elastase, like trypsin and chymotrypsin, is a serine protease that also hydrolyses amides and esters. It is produced in the pancreas as an inactive zymogen, proelastase, and activated in the duodenum by trypsin. Elastase is distinctive in that it acts...

Biovision | eIF3, Rabbit Reticulocytes | P1318

eIF3 is the largest translation factor and consists of 12 subunits. Complex organization of eIF3 explains its role in almost all steps of translation initiation, including ribosomal subunit anti-association activity, ternary complex recruitment to the...

Biovision | eIF2, Rabbit Reticulocytes | P1317

eEF2 promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.Biovision | P1317 | eIF2 Rabbit Reticulocytes DataSheetBiomolecule/Target: eIF2Synonyms: N/AAlternates names: N/ATaglines: eIF2 is a...

Biovision | eEF2, Rabbit Reticulocytes | P1316

eEF2 promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.Biovision | P1316 | eEF2 Rabbit Reticulocytes DataSheetBiomolecule/Target: eEF2Synonyms: Elongation factor 2, EF-2, EEF2Alternates...

Biovision | eEF1A, Rabbit Reticulocytes | P1315

eEF1 promotes the GTP-dependent binding of elongator aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of...

Biovision | Dipeptidyl Peptidase IV, Human Placenta | 4709

Dipeptidyl Peptidase IV is a lymphocyte cell surface antigen which is increased during T-cell activation and is also expressed in other tissues, such as placenta, kidney, etc. It is an atypical serine protease which has been implicated in a variety of...

Biovision | Defensins, Alpha, Mixed from Human Neutrophils (HNP, Human Neutrophil Peptides) | 7289

Alpha defensins are a family of mammalian defensin peptides. In general, defensins are small cysteine-rich cationic proteins found in both vertebrates and invertebrates. These mixed alpha defensins are purified from human neutrophils. These peptides are...

Biovision | Chymotrypsin, Human Pancreas | 7538

Chymotrypsin is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. Molecular weight of this enzyme is found to be 25...

Biovision | Chylomicrons, Human Plasma | 7285

Chylomicrons are the large triglyceride-rich lipoproteins of enteric origin that carry exogenous triglycerides into the plasma. Circulation of chylomicrons distributes dietary triglyceride to adipose tissue and to muscle. Found in post prandial plasma,...

Biovision | Chorionic Gonadotropin (CG), human | 4778

BioVision’s hCG is biologically active compared to standard. The biological activity of hCG is determined by using the seminal vesicle weight gain test in male rats described in the "Chorionic Gonadotrophins" monograph of the European Pharmacopoeia. The...

Biovision | Ceruloplasmin, Human Plasma | 4096

An acute-phase reactant. Increased levels are associated with normal pregnancy, rheumatoid arthritis, and cirrhosis. Decreased levels are associated with hepatolenticular degeneration (Wilson's Disease). An elevated level of Cp is found in patients with...

Biovision | Cathepsin H (active, human) | 1023

A more basic protein than Cathepsin B or L. Functions as both an aminopeptidase and endopeptidase. Cathepsin H, like cathepsin L and B, is involved in the catabolism of proteins in the lysosomal system.Biovision | 1023 | Cathepsin H active human...

Biovision | Cathepsin G, Human Neutrophil | 4713

Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It...

Biovision | Cathepsin D (active, human) | 1022

Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally cathepsin D has been associated...

Biovision | Cathepsin B (active, human) | 1021

Cathepsin B is a lysosomal cysteine protease. It is implicated in playing a role in protein degradation, arthritis, apoptosis, and cancer.Biovision | 1021 | Cathepsin B active human DataSheetBiomolecule/Target: Cathepsin BSynonyms: Cathepsin B (active,...

Biovision | Catalase, Human Erythrocytes | 4712

Composed of four identical subunits each with a molecular weight of 59,700. Catalyzes the reaction 2HO to HO+O. Catalase, along with the superoxides dismutase and glutathione peroxidase, controls the levels of oxygen-derived free radicals in mammalian...

Biovision | C1 Esterase inhibitor, Human Plasma | 7299

A single chain glycoprotein which inhibits C1, C1r, C1s, plasma kallikrein, Factors XIa. XIIa, and plasmin. Present in plasma at 16-33 mg per 100 ml. C1 esterase inhibitor deficiency is a rare condition resulting in facial swelling and abdominal cramping...

Biovision | Azurocidin, Human Neutrophil (Cationic protein 37) | 7287

The gene for azurocidin is located on the short arm of chromosome 19 and is in a cluster with the genes for proteinase 3 and elastase. All three proteins are serine protease homologues; azurocidin, however, lacks enzymatic activity. It is an antibiotic...

Biovision | Aspartate Aminotransferase (AST, GOT), Human Liver | P1299

AST/SGOT is found in many tissues throughout the body, including the liver, heart, muscles, kidney, and brain. If any of these organs or tissues is affected by disease or injury, AST is released into the bloodstream. This means that AST isn't as specific...

Biovision | Apotransferrin, Rat Plasma | 7541

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and...

Biovision | Apotransferrin, Mouse Plasma | 7540

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and...

Biovision | Apotransferrin, Human Plasma | 4707

Transferrin less the iron molecule. Like transferrin, apotransferrin has a physiological role in the transportation and distribution of iron among the body organs. It is also an important transport factor used in defined culture media. Purified...

Biovision | Apolipoprotein E, Human Plasma | 7284

Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell growth modulation and differentiation. Apo E is thought...

Biovision | Apolipoprotein CIII, Human Plasma | 4706

Apo CIII inhibits the activation of lipoprotein lipase by Apo CII. Reduced levels of Apo CIII result in higher fatty acid uptake from plasma triglycerides into adipose tissue. Thus, Apo CIII is a potential target for treatment of obesity and insulin...

Biovision | Apolipoprotein CII, Human Plasma | 4704

Apo CII activates lipoprotein lipase which then hydrolyzes VLDL triglyceride to form IDL (intermediate density lipoproteins). The concentration of Apo CII in normal plasma is 3-8 mg per 100 ml.Biovision | 4704 | Apolipoprotein CII Human Plasma...

Biovision | Apolipoprotein CI, Human Plasma | 4703

Apolipoprotein CI is one of the protein components of VLDL lipoprotein. The normal plasma concentration of Apo CI is 4-7 mg per 100 ml. Elevated levels of Apo CI may offer some protection from obesity and insulin-dependent diabetes. Some evidence exists...

Biovision | Apolipoprotein B, Human Plasma | 7283

Apolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90 mg per 100 ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids...

Biovision | Apolipoprotein AIV, Human Plasma | 7282

Apolipoprotein AIV (Apo AIV) is a glycoprotein synthesized by the human intestine. Synthesis appears to be stimulated by the absorption of high density lipoproteins that are rich in triglycerides rather than by the uptake or re-esterification of fatty...

Biovision | Apolipoprotein AII, Human Plasma | 7281

APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as...

Biovision | Alpha 2 Macroglobulin, Human Plasma, Fast Form | 7297

Alpha 2 Macroglobulin (A2M) is a plasma protease inhibitor which has been shown to exist in two forms. The Slow Form of A2M (S-A2M) is the form which possesses the ability to bind and inhibit proteases by a “trap” method. The Fast Form of A2M (F-A2M) is...

Biovision | Alpha 2 Macroglobulin, Human Plasma | 7296

Alpha 2 macroglobulin (A2M) is a major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. It functions as a broad-spectrum protease-binding protein. It is produced by the liver, and is a major component of...

Biovision | Alpha 2 HS Glycoprotein, Human Plasma | 7548

Found in human serum at 60 mg per 100 ml. This protein is a negative acute-phase reactant. Clinically, concentrations are reduced in cancer patients. AHSG levels are positively correlated with gestational diabetes and negatively correlated with neonatal...

Biovision | Alpha 2 Antiplasmin, Human Plasma | 7295

Alpha 2 Antiplasmin is a member of the Serpin superfamily and the primary physiological inhibitor of the serine protease plasmin, which is responsible for the dissolution of fibrin clots. In addition to plasmin, it is also an efficient inhibitor of...

Biovision | Alpha 1 Antitrypsin, Human Plasma | 7294

Alpha 1 Antitrypsin is an acute-phase plasma protein found at 290 mg per 100 ml. It functions as a serine protease inhibitor with targets like elastase, plasmin, collagenase, thrombin, leucocyte proteases, trypsin, chymotrypsin, and plasminogen activator...

Biovision | Alpha 1 Antichymotrypsin, Human Plasma | 7293

Alpha 1 antichymotrypsin is an acute-phase plasma protein found at 45 mg per 100 ml. ACT functions as a specific inhibitor of chymotrypsin-like serine proteases. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and...