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Product Description
FDFT1 polyclonal Antibody | BS7976 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FDFT1 polyclonal Antibody detects endogenous levels of FDFT1 protein.
Molecular Weight: ~ 48 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DGPT; ERG9; Farnesyl diphosphate farnesyltransferase 1; Farnesyl diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; FDFT_HUMAN; FDFT1; FPP:FPP farnesyltransferase; Presqualene di diphosphate synthase; SQS; Squalene synthase; Squalene synthetase; SS;
Immunogen: Recombinant full length Human FDFT1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
