Product Description
Anti-DHFR (Dihydrofolate reductase) monoclonal Antibody | MB62216 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: IF, IHC, WB
Application Range: WB 1:2000 IHC 1:50 IF 1:100
Background: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: dihydrofolate reductase
Molecular Weight: 21.5 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DHFRP1; DYR
Immunogen: Full-length protein expressed in 293T cell transfected with human DHFR expression vector
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A