Product Description
Anti-KDM4C monoclonal Antibody | MB62289 | Bioworld
Host: Mouse
Reactivity: Human, Rat
Application: IF, IHC, WB
Application Range: WB 1:2000, IHC 1:50, IF 1:100
Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: lysine demethylase 4C
Molecular Weight: 120.0 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GASC1; JHDM3C; JMJD2C; TDRD14C
Immunogen: Full-length protein expressed in 293T cell transfected with human KDM4C expression vector
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A