Product Description
Human CD28 (3G5E) monoclonal Antibody | EP0028 | Bioworld
Host: Mouse
Reactivity: Human
Application: FCM IHC-Fr IP T cell Co-stimulation
Application Range: Flow Cytometry (5 µg/ml) Frozen Sections (User-optimized) Immunoprecipitation (User-optimized) T cell Co-stimulation (User-optimized)
Background: Human CD28 is an important co-stimulatory molecule found on all CD4+ T cells and ~50% of CD8+ T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA, and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, known as CD80 (B7-1) and CD86 (B7-2), are monomeric transmembrane glycoproteins.
Storage & Stability: Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles.
Specificity: Recognizes the CD28 protein.
Molecular Weight: ~ 25 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: T-cell-specific surface glycoprotein CD28; TP44; CD28
Immunogen: Human CD28 Ig fusion protein and HPB-MLT human tumor cells.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A purified mouse monoclonal Antibody, >95% immunoglobulin by SDS-PAGE
Pathway: Neuronal and Glial Cell Marker Atlas,