Product Description
NFIB/NF1B2 monoclonal Antibody | MB9384 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC FC
Application Range: IHC:1:50-1:200 FC:1:50-1:100
Background: NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: NFIB/NF1B2 monoclonal Antibody detects endogenous levels of NFIB/NF1B2 protein.
Molecular Weight: 47 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: NF1-B, Nuclear factor 1/B, CTF, NF-I/B, NFI-B, NFIB, CCAAT Box Binding Transcription Factor, CCAAT-box-binding transcription factor, CTF, HMGIC/NFIB, NF-I/B, NF1-B, NF1B, NF1B2, NFI-B, NFI-RED, Nfib, NFIB, NFIB2, NFIB3, Nuclear factor 1 B-type, Nuclear factor 1/B, Nuclear Factor 1B, Nuclear Factor I B, Nuclear factor I/B, TGGCA Binding Protein, TGGCA-binding protein, TRANSCRIPTION FACTOR NFIB,
Immunogen: Recombinant full length protein corresponding to human NFIB/NF1B2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein affinity purified.
Pathway: