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Product Description
PDGFRA monoclonal Antibody | MB64418 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC, WB
Application Range: WB 1:2000, IHC 1:150
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: platelet derived growth factor receptor alpha
Molecular Weight: 120.3 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CD140A; GAS9; PDGFR-2; PDGFR2; RHEPDGFRA
Immunogen: Human recombinant protein fragment corresponding to amino acids 789-1089 of human PDGFRA (NP_006197) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
