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Product Description
TNNT2 monoclonal Antibody | MB65434 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC, WB
Application Range: WB 1:2000, IHC 1:150
Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM) . [provided by RefSeq, Jul
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: troponin T2, cardiac type
Molecular Weight: 35.4 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Immunogen: Native troponin complex
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
