Product Description
CD1E polyclonal Antibody | BS5652 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB ICC
Application Range: WB: 1:500~1:1000 ICC: 1:50~1:200
Background: CD1E, also known as R2 or CD1A, is a 322 amino acid single-pass type I membrane protein that localizes to the lumen of the endoplasmic reticulum, as well as to the golgi apparatus, and contains one Ig-like domain. Expressed in a variety of tissues and on cortical thymocytes, dendritic cells and Langerhans cells, CD1E exists as a heterodimer with β-2-Microglobulin and is necessary for the presentation of glycolipid antigens on the cell surface. CD1E is subject to post-translational mono-ubiquitination and may also be proteolytically cleaved in endosomes to yield a soluble protein. CD1E is present on the surface of some T-cell leukemias, suggesting a possible role in tumorigenesis.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD1E polyclonal Antibody detects endogenous levels of CD1E protein.
Molecular Weight: ~ 44 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: T-cell surface glycoprotein CD1e, membrane-associated; hCD1e; R2G1; CD1e; T-cell surface glycoprotein CD1e, soluble; sCD1e
Immunogen: Synthetic peptide, corresponding to amino acids 258-303 of Human CD1E.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: