Product Description
Desmin (V56) polyclonal Antibody | BS1860 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. Intermediate filaments are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. One such intermediate filament protein, Vimentin, is a general marker of cells originating in the mesenchyme. Vimentin is frequently co-expressed with other members of the intermediate filament family such as the cytokeratins,in neoplasms including melanoma and breast carcinoma. Vimentin and Desmin, a related class III intermediate filament, are both expressed during skeletal muscle development.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Desmin (V56) polyclonal Antibody detects endogenous levels of Desmin protein.
Molecular Weight: ~ 54 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: DES
Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human Desmin.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: