Product Description
HoxD12 (E230) polyclonal Antibody | BS2651 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD12 functions as a sequencespecific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: HoxD12 (E230) polyclonal Antibody detects endogenous levels of HoxD12 protein.
Molecular Weight: ~ 30 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Homeobox protein Hox-D12; Homeobox protein Hox-4H; HOXD12; HOX4H
Immunogen: Synthetic peptide, corresponding to amino acids 200-250 of Human HoxD12.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: