Product Description
RNASE1 polyclonal Antibody | BS7958 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB 1:500 - 1:2000
Background: RNase1 (ribonuclease, RNase A family, 1 (pancreatic), Rib1) gene encodes a 156 amino acid member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. RNase 1 endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. RNase 1 prefers poly (C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. RNase 1 is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. RNase1 is a digestive enzyme that has been recognized to be one of the most attractive model systems for molecular evolutionary studies. The RNase1 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 14q11.2, where it is linked to seven other RNase A superfamily genes. The entire RNase A cluster spans 368 kb.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RNASE1 polyclonal Antibody detects endogenous levels of RNASE1 protein.
Molecular Weight: ~ 18 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: HP-RNase; Pancreatic ribonuclease; Rib 1; RIB-1; Rib1; Ribonuclease 1; Ribonuclease A; Ribonuclease a family 1; Ribonuclease pancreatic; Ribonuclease RNase A family 1; Ribonuclease RNase A family 1 pancreatic; RNAS1_HUMAN; RNase 1; RNase A; RNase UpI-1; Rnase1; RNAseA;
Immunogen: Recombinant full length Human RNASE1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Immune Cell Signaling,Toll-like Receptor signaling,