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Product Description
Spindlin-1 (H139) polyclonal Antibody | BS2678 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Spindlin-1 (H139) polyclonal Antibody detects endogenous levels of Spindlin-1 protein.
Molecular Weight: ~ 30 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: OCR; Ovarian cancer-related protein; SPIN; Spin1; SPIN1; Spindlin 1;
Immunogen: Synthetic peptide, corresponding to amino acids 110-156 of Human Spindlin-1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
