Product Description
ZC3H8 polyclonal Antibody | BS5770 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (by similarity) . ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ZC3H8 polyclonal Antibody detects endogenous levels of ZC3H8 protein.
Molecular Weight: ~ 33 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Zinc finger CCCH domain-containing protein 8; ZC3HDC8
Immunogen: Synthetic peptide, corresponding to amino acids 133-178 of Human ZC3H8.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: