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Product Description
ATRIP (D64) polyclonal Antibody | BS1510 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC IF
Application Range: IHC: 1:50~1:200 IF: 1:50~1:200
Background: The product of the ATRIP gene is an essential component of the DNA damage checkpoint, and binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ATRIP (D64) polyclonal Antibody detects endogenous levels of ATRIP protein.
Molecular Weight: ~ 80 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ATR-interacting protein; ATM and Rad3-related-interacting protein; ATRIP; AGS1
Immunogen: Synthetic peptide, corresponding to amino acids 30-76 of Human ATRIP.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Regulation of Apoptosis,Inhibition of Apoptosis,Mitochondrial Control of Apoptosis,Death Receptor Signaling,
