Product Description
ATRIP polyclonal Antibody | BS8739 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IP
Application Range: WB 1:500 - 1:2000 IP 1:50 - 1:200
Background: The product of the ATRIP gene is an essential component of the DNA damage checkpoint, and binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ATRIP polyclonal Antibody detects endogenous levels of ATRIP protein.
Molecular Weight: ~ 86kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ATR-interacting protein; ATM and Rad3-related-interacting protein; ATRIP; AGS1
Immunogen: Recombinant full length Human ATRIP.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: