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Product Description
CASP8AP2 polyclonal Antibody | BS72749 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB 1:500 - 1:2000
Background: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CASP8AP2 polyclonal Antibody detects endogenous levels of CASP8AP2 protein.
Molecular Weight: 215kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CED-4;FLASH;RIP25
Immunogen: Recombinant protein of human CASP8AP2
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
