Product Description
CBFA2T3 polyclonal Antibody | BS72475 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB
Application Range: WB 1:500 - 1:2000
Background: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t (16;21) (q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CBFA2T3 polyclonal Antibody detects endogenous levels of CBFA2T3 protein.
Molecular Weight: ~ 60 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ETO2;MTG16;MTGR2;RUNX1T3;ZMYND4
Immunogen: Recombinant protein of human CBFA2T3
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: