Product Description
MNK1 (Phospho-Thr250) polyclonal Antibody | BS65149 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC-p,IF (paraffin section),ELISA
Application Range: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Background: MAP kinase interacting serine/threonine kinase 1 (MKNK1) Homo sapiens This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012],
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Phospho-Mnk1 (T250) Polyclonal Antibody detects endogenous levels of Mnk1 protein only when phosphorylated at T250.
Molecular Weight: /
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: MKNK1; MNK1; MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1
Immunogen: The antiserum was produced against synthesized peptide derived from human MNK1 around the phosphorylation site of Thr250. AA range:216-265
Conjugate: Unconjugated
Modification: Phosphorylation
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: