Product Description
PRCC monoclonal Antibody | MB64617 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: WB
Application Range: WB 1:500
Background: This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1) (p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: papillary renal cell carcinoma (translocation-associated)
Molecular Weight: 52.2 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: RCCP1; TPRC
Immunogen: Human recombinant protein fragment corresponding to amino acids 135-491 of human PRCC (NP_005964) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A