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Product Description
STARD4 monoclonal Antibody | MB65260 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: WB
Application Range: WB 1:2000
Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE) -binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617) . STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]) . [supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: AK054566.1, AK290312.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END##
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: StAR related lipid transfer domain containing 4
Molecular Weight: 23.3 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 4632419C16Rik; 9030213J02Rik; AA517649; AW324468; StAR-related lipid transfer (START) domain containing 4; StAR-related lipid transfer protein 4
Immunogen: Full length human recombinant protein of human STARD4 (NP_631903) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
