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Product Description
EIF4B polyclonal Antibody | BS7572 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IHC IF IP
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:200
Background: Eukaryotic initiation factor 4B (eIF4B) is thought to assist the eIF4F complex in translation initiation. In plants, eIF4B is known to interact with the poly- (A) binding protein, increasing its poly- (A) binding activity. Heat shock and serum starvation cause dephosphorylation of eIF4B at multiple sites with kinetics similar to those of the corresponding inhibition of translation, while phosphorylation of eIF4B following insulin treatment correlates well with an observed increase in translation.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: EIF4B polyclonal Antibody detects endogenous levels of EIF4B protein.
Molecular Weight: ~ 80 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Eukaryotic translation initiation factor 4B; eIF-4B; EIF4B
Immunogen: Recombinant full length Human EIF4B.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Regulation of Microtubule Dynamics,
