Product Description
ELAC2 polyclonal Antibody | BS8728 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB IHC IF
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200
Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ELAC2 polyclonal Antibody detects endogenous levels of ELAC2 protein.
Molecular Weight: ~ 105 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2; ELAC2; HPC2
Immunogen: Recombinant full length Human ELAC2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: