Product Description
FCAR polyclonal Antibody | BS60015 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens, such as microorganisms and pathogens, by removing Ig-coated antigen complexes from circulation. Fc receptors are present on lymphoid and myeloid derivatives, where they mediate endocytosis of Ig-antigen complexes, Antibody production in B cells through T cell antigen presentation, cytotoxicity, and the release of cytokines and reactive oxygen species. Human myeloid receptor for the Fc fragment of IgA (CD89) is a glycoprotein that is expressed on the surface of neutrophils, monocytes, macrophages and eosinophils and is a potent cytotoxic trigger molecule. Cytokines can initiate a highbinding state for CD89 through a mechanism that involves the intracellular C-terminus of CD89.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FCAR polyclonal Antibody detects endogenous levels of FCAR protein.
Molecular Weight: ~ 60 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Immunoglobulin alpha Fc receptor; IgA Fc receptor; FCAR; CD89
Immunogen: A synthetic peptide corresponding to residues in Human FCAR
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A