Product Description
KCNA1 polyclonal Antibody | BS65292 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
Application Range: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Background: potassium voltage-gated channel subfamily A member 1 (KCNA1) Homo sapiens This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD) . The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK) . [provided by RefSeq, Jul 2008]
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: KV1.1 Polyclonal Antibody detects endogenous levels of KV1.1 protein.
Molecular Weight: ~ 57 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K (+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1
Immunogen: The antiserum was produced against synthesized peptide derived from human KCNA1. AA range:256-305
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: