Product Description
NFATC1 polyclonal Antibody | BS6677 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: NFATc1 is present in uninduced cells and translocates to the nucleus upon calcium mobilization. The phosphatase calcineurin promotes nuclear accumulation of NF-ATc. PKA causes phosphorylation and cytoplasmic accumulation of NF-ATc1 in direct opposition to calcineurin by phosphorylating Ser-245, Ser-269, and Ser-294 in the conserved serine-proline repeat domain.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NFATC1 polyclonal Antibody detects endogenous levels of NFATC1 protein.
Molecular Weight: ~ 78 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: cytoplasmic 1; MGC138448; NF ATc; NF ATc1; NF-ATc; NF-ATc1; NFAC1; NFAT 2; NFAT transcription complex cytosolic component; NFAT2; NFATC 1; NFATc; NFATc1; Nuclear factor of activated T cells cytoplasmic 1; Nuclear factor of activated T-cells;
Immunogen: Recombinant full length Human NFATC1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: