Product Description
NR4A3 polyclonal Antibody | BS65254 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB,ELISA
Application Range: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Background: nuclear receptor subfamily 4 group A member 3 (NR4A3) Homo sapiens This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE) . Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15) . Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NOR-1 Polyclonal Antibody detects endogenous levels of NOR-1 protein.
Molecular Weight: ~ 65 kDa
Note: For
Alternative Names: NR4A3; CHN; CSMF; MINOR; NOR1; TEC; Nuclear receptor subfamily 4 group A member 3; Mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; Nuclear hormone receptor NOR-1
Immunogen: The antiserum was produced against synthesized peptide derived from human NR4A3. AA range:387-436
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: SAPK JNK Signaling Cascades,