Product Description
PGGT1B Polyclonal Antibody | BS65460 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat,Horse,
Application: WB,
Application Range: WB=1:500-2000
Background: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]) . The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PGGT1B Polyclonal Antibody detects endogenous levels of PGGT1B protein.
Molecular Weight: 42 kD
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PGGT1B; GGTase-I beta; GGTase-1 beta; BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Type I protein geranyl-geranyltransferase subunit beta;
Immunogen: KLH conjugated synthetic peptide derived from human PGGT1 beta:301-377/377
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: affinity purified by Protein A
Pathway: