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Product Description
phospho-RACGAP1 (Ser387) Polyclonal Antibody | BS65993 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat,Dog,Cow,
Application: WB,
Application Range: WB=1:500-2000
Background: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: phospho-RACGAP1 (Ser387) Polyclonal Antibody detects endogenous levels of RACGAP1 alpha protein only when phosphorylated at Ser387.
Molecular Weight: 71kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: RACGAP1 (phospho S387) ; p-RACGAP1 (S387) ; p-RACGAP1 (Ser387) ; GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.
Immunogen: KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387:RI (p-S) GC
Conjugate: Unconjugated
Modification: Phosphorylation
Purification & Purity: affinity purified by Protein A
Pathway:
