Product Description
RNF14 polyclonal Antibody | BS65257 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB,ELISA
Application Range: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Background: ring finger protein 14 (RNF14) Homo sapiens The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011],
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ARA54 Polyclonal Antibody detects endogenous levels of ARA54 protein.
Molecular Weight: ~ 50 kDa
Note: For
Alternative Names: RNF14; ARA54; HRIHFB2038; E3 ubiquitin-protein ligase RNF14; Androgen receptor-associated protein 54; HFB30; RING finger protein 14; Triad2 protein
Immunogen: The antiserum was produced against synthesized peptide derived from human RNF14. AA range:361-410
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: