Product Description
SIRPB1 polyclonal Antibody | BS65298 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB,ELISA
Application Range: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Background: signal regulatory protein beta 1 (SIRPB1) Homo sapiens The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.
Molecular Weight: ~ 48 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: SIRPB1; Signal-regulatory protein beta-1; SIRP-beta-1; CD172 antigen-like family member B; CD antigen CD172b
Immunogen: The antiserum was produced against synthesized peptide derived from human SIRPB1. AA range:231-280
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: