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Product Description
BTNL2 polyclonal Antibody | BS8723 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IHC
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200
Background: BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: BTNL2 polyclonal Antibody detects endogenous levels of BTNL2 protein.
Molecular Weight: ~ 50kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Butyrophilin-like protein 2; BTL-II; BTNL2
Immunogen: Recombinant full length Human BTNL2.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A
