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Product Description
GPD1 polyclonal Antibody | BS7810 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200
Background: Voltage-gated sodium channels drive the initial depolarization phase of the cardiac action potential, therefore, critically determine conduction of excitation through the heart. As a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family, glycerol-3-phosphate dehydrogenase 1 (GPD1) is a 349 amino acid cytoplasmic protein that catalyzes the formation of glycerone phosphate and NADH from sn-glycerol 3-phosphate and NAD+. Inhibited by zinc ions and sulfate, GPD1 exists as a homodimer and may have similar functions as GPD1L (glycerol-3 phosphate dehydrogenase like) . GPD1L is thought to affect trafficking of the cardiac sodium current to the cell surface and mutations in the gene encoding GPD1L are thought to be involved in sudden infant death syndrome (SIDS) .
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GPD1 polyclonal Antibody detects endogenous levels of GPD1 protein.
Molecular Weight: ~ 38 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: cytoplasmic; FLJ26652; G3PD; Gdc-1; Gdc1; Gdp1; Glycerol 3 phosphate dehydrogenase 1; Glycerol 3 phosphate dehydrogenase cytosolic; Glycerol 3 phosphate dehydrogenase soluble; Glycerol-3-phosphate dehydrogenase [NAD+]; Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; Glycerol-3-phosphate dehydrogenase 1 (soluble) ; Glycerol-3-phosphate dehydrogenase; Glycerol-3-phosphate dehydrogenase, soluble; Glycerphosphate dehydrogenase; GPD-C; gpd1; Gpd1 protein; Gpd3; GPDA_HUMAN; Gpdc; GPDH; GPDH-C; Gpdhc; HTGTI; KIAA4010; MGPD; mKIAA4010;
Immunogen: Recombinant full length Human GPD1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
