Product Description
GRB2 monoclonal Antibody | MB9247 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: WB IHC ICC
Application Range: WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200
Background: Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene. The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the sem-5 gene of Caenorhabditis elegans, which is involved in the signal transduction pathway.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: GRB2 monoclonal Antibody detects endogenous levels of GRB2 protein.
Molecular Weight: 25 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GRB2, ASH, Abundant SRC homology, Adapter protein GRB2, ASH, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb2, GRB2, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, Growth factor receptor-bound protein 2, HT027, MST084, MSTP084, NCKAP2, OTTHUMP00000166096, OTTHUMP00000166097, OTTHUMP00000166098, Protein ash, SEM5, SH2/SH3 adapter GRB2,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProG affinity purified
Pathway: