Product Description
IARS polyclonal Antibody | BS70334 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:100
Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IARS polyclonal Antibody detects endogenous levels of IARS protein.
Molecular Weight: ~ 144 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Isoleucine--tRNA ligase, cytoplasmic; Isoleucyl-tRNA synthetasel; IleRS
Immunogen: Recombinant protein of human IARS.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Neuronal and Glial Cell Marker Atlas,Vesicle Trafficking presynaptic signaling,AMPK Signaling Pathway,