Product Description
FH (Fumarate Hydratase) monoclonal Antibody | MB63300 | Bioworld
Host: Mouse
Reactivity: Human, Mouse, Rat, Dog
Application: IF, WB
Application Range: WB 1:2000, IF 1:50~100
Background: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]
Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: fumarate hydratase
Molecular Weight: 50.2 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FMRD; HLRCC; LRCC; MCL; MCUL1
Immunogen: Full length human recombinant protein of human FH (NP_000134) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A