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Product Description
hnRNP A1 polyclonal Antibody | BS90654 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse,Rat
Application: WB ICC IHC FC
Application Range: WB:1:500-1:2,000 ICC:1:50-1:200
Background: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. The A/B subfamily of hnRNPs include A1, A2/B1, A3 and A0, and in Xenopus, hnRNP A1, A2 and A3 are ubiquitously expressed throughout development as well as in adult tissues. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The hnRNP A0 gene is distinct from the other A/B family members, and it encodes a low-abundance protein, which is implicated in mRNA stability.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: hnRNP A1 polyclonal Antibody detects endogenous levels of hnRNP A1 protein.
Molecular Weight: 33 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: HNRNPA1, HNRPA1, HNRNPA 1, Helix destabilizing protein, Helix-destabilizing protein, Heterogeneous nuclear ribonucleoprotein A1, Heterogeneous nuclear ribonucleoprotein A1B protein, Heterogeneous nuclear ribonucleoprotein B2 protein, Heterogeneous nuclear ribonucleoprotein core protein A1, hnRNP A1, hnRNP core protein A1, HNRNPA1, HNRPA1, MGC102835, Nuclear ribonucleoprotein particle A1 protein, ROA1, Single strand DNA binding protein UP1, Single strand RNA binding protein, Single-strand RNA-binding protein,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway:
